Coronavirus hotspots: Sheffield, Slough, London and Birmingham

UK’s coronavirus hotspots: Sheffield, Birmingham and Slough have the most cases of the killer infection per 100,000 people than everywhere in England except London

  • London has the highest infection rate with 64 cases per 100,000 people
  • Its followed by Sheffield, in South Yorkshire, with 52 cases per 100,000
  • Slough, a town just 20 miles from London, has 49 cases per 100,000
  • The figures have been collated to represent the ratio of infected to healthy 
  • Coronavirus symptoms: what are they and should you see a doctor?

Sheffield, Birmingham and Slough are three of the UK’s coronavirus hotspots, with more cases per population than everywhere except London. 

The capital has the highest COVID-19 infection rate – 64 cases per 100,000 people, followed by Sheffield (52).

Birmingham is third with 50. And Slough, a town in Berkshire just 20 miles west of London, has 49 cases for every 100,000 people. 

The true size of the UK’s coronavirus outbreak remains a mystery because of the controversial policy to only test patients in hospital.  

Only 22,000 cases have been officially diagnosed – but scientists have suggested the true toll could be in the millions. 

Sheffield and Slough are coronavirus hotspots in the UK, not far behind London which continues to speed ahead. London has 64 cases per 100,000 people, followed by Sheffield, in South Yorkshire, with 52 cases. Birmingham is third with 50 cases per 100,000, followed by Slough, a town in Berkshire, with 49 cases per 100,000

Figures from Public Health England (PHE) can be broken down into local authorities to show which have the most cases of coronavirus.

London and Birmingham have the most – 6,521 and 578 cases, respectively. Almost 500 cases have been recorded in Hampshire and 428 in Sheffield.

But Centre for Cities take a different approach to collating the PHE figures, looking at the number of coronavirus cases per 100,000 people.

It gives a clearer idea of how each area is being impacted by the epidemic, with a higher figure indicating there are more infected people among the population. 


By cases per 100,000 people  

By total cases

Slough has 73 total cases of coronavirus, but 59 cases per 100,000 is a high ratio considering its population of some 164,000.

In comparison, London, with a population of almost nine million, has 64 cases per 100,000. Birmingham, 126 miles away from the capital, has 50 cases per 100,000 for its population of around one million. 

Liverpool and Manchester, both with around half a million residents, have been less severely impacted by the coronavirus, with 30 and 36 cases per 100,000 respectively. 

But Sheffield, also with around half a million people, has a record high 59 cases per 100,000 – not far behind the far larger London. 

Derby, with at least a quarter of a million residents has more cases per 100,000 (49) than both Liverpool and Manchester. Overall, it has a total of 118 recorded cases.

Milton Keynes (35) and Luton (32), both near to London, have a higher ratio of infection per 100,000 than Liverpool. Each have 94 and 69 reported cases respectively. 

Hull has the lowest number of cases per population, with around three confirmed cases per 100,000 inhabitants. It has a total of 11 cases, according to PHE. 

Eastern parts of Berkshire, including Slough, are worst affected. They are closest to London, which may suggest a spread from the city. Pictured, a deserted shopping centre in Slough

Birmingham has the third most cases per 100,000 (50). Pictured, a fruit and vegetable trader serves a customer at a market in the city on March 24

To ease pressure on NHS hospitals in the West Midlands, The National Exhibition Centre in Birmingham is being set up as a temporary hospital to treat patients without COVID-19

Scientists have attributed the large proportion of ‘total cases’ in London and Birmingham to its dense population and the fact they are international travel hubs.

The movement of large numbers of people, some tourists from hard-hit countries, would have contributed to the influx of cases in the first instance.

But it’s unclear why Slough and Sheffield have been implicated so severely.

On March 17, the deadly virus had only infected two people in Slough and Sheffield didn’t have any cases at all.

Between then and now, there has been an unprecedented rise in both areas, increasing far quicker than other cities of similar size. 

Sheffield Teaching Hospitals Foundation Trust has reported 15 deaths from the coronavirus. 

Director of Public Health for Sheffield, Greg Fell, said the region’s numbers could be down to increased frequency of tests in the city, The Star reported.

Mr Fell said on March 26: ‘I understand that people may find the reported number of cases in Sheffield worrying, but the data is simply a reflection that there is more testing happening here currently than in some other areas and so by default we know about more positive cases.

‘This doesn’t necessarily mean that there’s more chance of being infected here than other parts of Yorkshire.’

It’s not clear why people in Sheffield are being tested more than other areas, as Mr Fell suggests. 

Slough is part of Berkshire, which in total has recorded 234 cases and one death. 

Figures show the eastern parts of the county, which are the worst affected, are closest to London, which may suggest a spread from the city.  

Meanwhile, the Midlands has been considered a hotspot of cases for some time, encompassing Birmingham and Derby.

Health Secretary Matt Hancock said the Government were investigating why.

To ease pressure on NHS hospitals in the West Midlands, The National Exhibition Centre in Birmingham is being set up as a temporary hospital to treat non-urgent patients without COVID-19. 

It is thought the centre will open with 500 beds, with space to house 2,000 should demand grow.

The UK’s overall death toll hit more than 1,400 yesterday, but figures being released today will reveal it is higher when taking into account those who have died in their own homes or residential care.

There are more than 220,000 cases overall, which will increase again once the latest figures are reported this afternoon.


What is the coronavirus? 

A coronavirus is a type of virus which can cause illness in animals and people. Viruses break into cells inside their host and use them to reproduce itself and disrupt the body’s normal functions. Coronaviruses are named after the Latin word ‘corona’, which means crown, because they are encased by a spiked shell which resembles a royal crown.

The coronavirus from Wuhan is one which has never been seen before this outbreak. It has been named SARS-CoV-2 by the International Committee on Taxonomy of Viruses. The name stands for Severe Acute Respiratory Syndrome coronavirus 2.

Experts say the bug, which has killed around one in 50 patients since the outbreak began in December, is a ‘sister’ of the SARS illness which hit China in 2002, so has been named after it.

The disease that the virus causes has been named COVID-19, which stands for coronavirus disease 2019.

Dr Helena Maier, from the Pirbright Institute, said: ‘Coronaviruses are a family of viruses that infect a wide range of different species including humans, cattle, pigs, chickens, dogs, cats and wild animals. 

‘Until this new coronavirus was identified, there were only six different coronaviruses known to infect humans. Four of these cause a mild common cold-type illness, but since 2002 there has been the emergence of two new coronaviruses that can infect humans and result in more severe disease (Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) coronaviruses). 

‘Coronaviruses are known to be able to occasionally jump from one species to another and that is what happened in the case of SARS, MERS and the new coronavirus. The animal origin of the new coronavirus is not yet known.’ 

The first human cases were publicly reported from the Chinese city of Wuhan, where approximately 11million people live, after medics first started publicly reporting infections on December 31.

By January 8, 59 suspected cases had been reported and seven people were in critical condition. Tests were developed for the new virus and recorded cases started to surge.

The first person died that week and, by January 16, two were dead and 41 cases were confirmed. The next day, scientists predicted that 1,700 people had become infected, possibly up to 7,000. 

Where does the virus come from?

According to scientists, the virus almost certainly came from bats. Coronaviruses in general tend to originate in animals – the similar SARS and MERS viruses are believed to have originated in civet cats and camels, respectively.

The first cases of COVID-19 came from people visiting or working in a live animal market in Wuhan, which has since been closed down for investigation.

Although the market is officially a seafood market, other dead and living animals were being sold there, including wolf cubs, salamanders, snakes, peacocks, porcupines and camel meat. 

A study by the Wuhan Institute of Virology, published in February 2020 in the scientific journal Nature, found that the genetic make-up virus samples found in patients in China is 96 per cent identical to a coronavirus they found in bats.

However, there were not many bats at the market so scientists say it was likely there was an animal which acted as a middle-man, contracting it from a bat before then transmitting it to a human. It has not yet been confirmed what type of animal this was.

Dr Michael Skinner, a virologist at Imperial College London, was not involved with the research but said: ‘The discovery definitely places the origin of nCoV in bats in China.

‘We still do not know whether another species served as an intermediate host to amplify the virus, and possibly even to bring it to the market, nor what species that host might have been.’  

So far the fatalities are quite low. Why are health experts so worried about it? 

Experts say the international community is concerned about the virus because so little is known about it and it appears to be spreading quickly.

It is similar to SARS, which infected 8,000 people and killed nearly 800 in an outbreak in Asia in 2003, in that it is a type of coronavirus which infects humans’ lungs. It is less deadly than SARS, however, which killed around one in 10 people, compared to approximately one in 50 for COVID-19.

Another reason for concern is that nobody has any immunity to the virus because they’ve never encountered it before. This means it may be able to cause more damage than viruses we come across often, like the flu or common cold.

Speaking at a briefing in January, Oxford University professor, Dr Peter Horby, said: ‘Novel viruses can spread much faster through the population than viruses which circulate all the time because we have no immunity to them.

‘Most seasonal flu viruses have a case fatality rate of less than one in 1,000 people. Here we’re talking about a virus where we don’t understand fully the severity spectrum but it’s possible the case fatality rate could be as high as two per cent.’

If the death rate is truly two per cent, that means two out of every 100 patients who get it will die. 

‘My feeling is it’s lower,’ Dr Horby added. ‘We’re probably missing this iceberg of milder cases. But that’s the current circumstance we’re in.

‘Two per cent case fatality rate is comparable to the Spanish Flu pandemic in 1918 so it is a significant concern globally.’

How does the virus spread?

The illness can spread between people just through coughs and sneezes, making it an extremely contagious infection. And it may also spread even before someone has symptoms.

It is believed to travel in the saliva and even through water in the eyes, therefore close contact, kissing, and sharing cutlery or utensils are all risky. It can also live on surfaces, such as plastic and steel, for up to 72 hours, meaning people can catch it by touching contaminated surfaces.

Originally, people were thought to be catching it from a live animal market in Wuhan city. But cases soon began to emerge in people who had never been there, which forced medics to realise it was spreading from person to person. 

What does the virus do to you? What are the symptoms?

Once someone has caught the COVID-19 virus it may take between two and 14 days, or even longer, for them to show any symptoms – but they may still be contagious during this time.

If and when they do become ill, typical signs include a runny nose, a cough, sore throat and a fever (high temperature). The vast majority of patients will recover from these without any issues, and many will need no medical help at all.

In a small group of patients, who seem mainly to be the elderly or those with long-term illnesses, it can lead to pneumonia. Pneumonia is an infection in which the insides of the lungs swell up and fill with fluid. It makes it increasingly difficult to breathe and, if left untreated, can be fatal and suffocate people.

Figures are showing that young children do not seem to be particularly badly affected by the virus, which they say is peculiar considering their susceptibility to flu, but it is not clear why. 

What have genetic tests revealed about the virus? 

Scientists in China have recorded the genetic sequences of around 19 strains of the virus and released them to experts working around the world. 

This allows others to study them, develop tests and potentially look into treating the illness they cause.   

Examinations have revealed the coronavirus did not change much – changing is known as mutating – much during the early stages of its spread.

However, the director-general of China’s Center for Disease Control and Prevention, Gao Fu, said the virus was mutating and adapting as it spread through people.

This means efforts to study the virus and to potentially control it may be made extra difficult because the virus might look different every time scientists analyse it.   

More study may be able to reveal whether the virus first infected a small number of people then change and spread from them, or whether there were various versions of the virus coming from animals which have developed separately.

How dangerous is the virus?  

The virus has a death rate of around two per cent. This is a similar death rate to the Spanish Flu outbreak which, in 1918, went on to kill around 50million people.

Experts have been conflicted since the beginning of the outbreak about whether the true number of people who are infected is significantly higher than the official numbers of recorded cases. Some people are expected to have such mild symptoms that they never even realise they are ill unless they’re tested, so only the more serious cases get discovered, making the death toll seem higher than it really is.

However, an investigation into government surveillance in China said it had found no reason to believe this was true.

Dr Bruce Aylward, a World Health Organization official who went on a mission to China, said there was no evidence that figures were only showing the tip of the iceberg, and said recording appeared to be accurate, Stat News reported.

Can the virus be cured? 

The COVID-19 virus cannot be cured and it is proving difficult to contain.

Antibiotics do not work against viruses, so they are out of the question. Antiviral drugs can work, but the process of understanding a virus then developing and producing drugs to treat it would take years and huge amounts of money.

No vaccine exists for the coronavirus yet and it’s not likely one will be developed in time to be of any use in this outbreak, for similar reasons to the above.

The National Institutes of Health in the US, and Baylor University in Waco, Texas, say they are working on a vaccine based on what they know about coronaviruses in general, using information from the SARS outbreak. But this may take a year or more to develop, according to Pharmaceutical Technology.

Currently, governments and health authorities are working to contain the virus and to care for patients who are sick and stop them infecting other people.

People who catch the illness are being quarantined in hospitals, where their symptoms can be treated and they will be away from the uninfected public.

And airports around the world are putting in place screening measures such as having doctors on-site, taking people’s temperatures to check for fevers and using thermal screening to spot those who might be ill (infection causes a raised temperature).

However, it can take weeks for symptoms to appear, so there is only a small likelihood that patients will be spotted up in an airport.

Is this outbreak an epidemic or a pandemic?   

The outbreak was declared a pandemic on March 11. A pandemic is defined by the World Health Organization as the ‘worldwide spread of a new disease’. 

Previously, the UN agency said most cases outside of Hubei had been ‘spillover’ from the epicentre, so the disease wasn’t actually spreading actively around the world.

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